Since joining HKRep in 2001, Karrie Tan has taken part in more than 100 productions. Recent productions include After Life, Stay with the Flow, The Doctor, Moscow Express, Sœurs, The Precious One. She has also participated in drama education and she is the Project Artistic Supervisor in Jockey Club ‘Sing Out’ Character Education Musical Project.She is also a member of the China Theatre Association.
 
She was awarded Best Actress (Tragedy/Drama) for Marriage at the Hong Kong Drama Awards in 2016, and Best Supporting Actress (Tragedy/Drama) for The Professor in 2014. In 2000, her performance in Steel Magnolias won her Best Supporting Actress (Tragedy/Drama) at the Hong Kong Drama Awards. She was nominated for Outstanding Actress at the 2nd and the 14th Hong Kong Theatre Libre Awards for The Labels and Sœurs respectively. Karrie has been frequently nominated as Best Actress or Best Supporting Actress at the Hong Kong Drama Awards.
 

In addition, her innovative creations and performances in HKRep Black Box — Those were the Days, The Labels (also as Deputy Director), A Hollow Room (also as Director) —have earned her much critical acclaim. In 2013, she collaborated with the Radiant Theatre as playwright and director for The Mixed Doubles, which was selected among the Top Ten Most Popular Productions at the 23rd Hong Kong Drama Awards. A Giant Cookie, a black box production which she wrote and directed, was nominated for Best Script at the 7th Hong Kong Theatre Libre in 2014.
  

In 2009, Karrie received Sir Robert Black Trust Fund Postgraduate Scholarships and studied at the Birmingham School of Acting, during which she received a Master’s degree in Drama with first class honours. She was selected as the Rising Star by The Stage (Theatre news). During her study in the United Kingdom, she took part in productions include Troilus and Cressida (as Cressida / Helen of Troy), Hedda Gabler (as Hedda) and The House of Yes (as Lesly)。
 

Apart from stage appearances, Tan has appeared in commercials and television programmes. She was also a Cantonese voice artist for Disney in the role of Susan Pevensie in The Chronicles of Narnia: The Lion, the Witch and the Wardrobe. She also performed in RTHK's Artspiration, A Wall-less World (The 5th episode), as well as ViuTV's Craft a Live.